Hannah R. Malcolm, Ph.D.
Hannah R. Malcolm, Ph.D. joined the Department of Chemistry at the University of North Florida in 2015 as an assistant professor. I completed my graduate work at Washington University in St. Louis in 2012, with Prof. Joshua A. Maurer. At WashU, my dissertation research focused on the bacterial cyclic nucleotide gated (bCNG) channel subfamily in the MscS superfamily of ion channels. I then completed my post-doctoral research at UT Southwestern with Prof. Paul Blount (2012-2015). In Professor Blount’s lab I focused on utilizing patch clamp electrophysiology to study E. coli MscS.
Since joining the UNF Department of Chemistry I have taught General Chemistry I (both lecture and lab) and Biochemistry I and II (both lecture and lab). I have a vibrant research program that explores how bacteria sense and respond to mechanical tension in the membrane. My research group focuses on bacterial mechanosensitive ion channels, specifically MscS (mechanosensitive channel of small conductance) and MscL (mechanosensitive channel of large conductance) as well as their homologues. We study these channels in E. coli, P. graminis, and other novel bacterial strains. We utilize several different techniques to understand how each of these channels responds to mechanical tension in the membrane.
The Lab Space
The Malcolm Lab is located on the third floor of the Science and Engineering building (Building 50). We have a bacterial patch clamp electrophysiology rig, a full suite of microbiology equipment, and access to the equipment in the department labs.