CV

Hannah R. Malcolm, Ph.D.
1 UNF Drive, Department of Chemistry 50/3400

Office 3130, Lab 3024
Jacksonville, FL 32224
Phone: 904-620-1963

email: Hannah.malcolm at Unf dot edu

EDUCATION

Ph. D., Chemistry, Washington University in St. Louis, St. Louis MO (2012)

A.M., Chemistry, Washington University in St. Louis, St. Louis, MO (2008)

B.S., Chemistry, Texas A&M University at College Station, College Station, TX (2006)

EXPERIENCE

Assistant Professor of Chemistry University of North Florida (August 2015- Present)

Postdoctoral Researcher, Department of Physiology, UT Southwestern Medical Center (May 2012- July 2015, Advisor: Professor Paul Blount)

Graduate Research Assistant, Department of Chemistry, Washington University in St. Louis (January 2007- May 2012, Advisor: Professor Joshua A. Maurer (now at Benet National Labs))

Undergraduate Research Assistant, Department of Biology, Texas A&M University at College Station (October 2002-May 2006, Advisor: Professor Susan S. Golden (now at UCSD))

PUBLICATIONS

* denotes equal contributions, ¶  denotes UNF student, § denotes corresponding author. HRM in bold.

  • Johnson, S.C. *¶, Veres, J. *¶, Malcolm, H.R. § Exploring the diversity of mechanosensitive channels in bacterial genomes (2021) European Biophysics Journal 50, 25-16
  • Miller B.L. *¶, Dickinson, H.M. * ¶, Wingender, B., Mikhaylova, A., Malcolm, H. R. § Characterizing the mechanosensitive response of Paraburkholderia graminis membranes (2020) BBA:Biomembranes 1862 (4) 183176
  • Malcolm, H. R. and Blount, P. § Mutations in a Conserved Domain of E. coli MscS to the Most Conserved Superfamily Residue Leads to Kinetic Changes PLoS One. (2015) 10(9): e0136756. doi:10.1371/journal.pone.0136756 PMID: 26340270 
  • Malcolm, H.R., Blount, P., Maurer, J.A. § The Mechanosensitive Channel of Small Conductance (MscS) Functions as a Jack-In-The-Box Biochim Biophys Acta: Biomembranes. (2015) 1848(1):159-166.
  • Malcolm, H.R., Heo, Y.Y., Elmore, D.E., Maurer, J.A. §, Heteromultimerization of Prokaryotic Bacterial Cyclic Nucleotide Gated (bCNG) Ion Channels, Members of the Mechanosensitive Channel of Small Conductance (MscS) Superfamily. Biochemistry (2014) 53(51):8005-8007.
  • Malcolm, H.R., Heo, Y.Y., Caldwell, D.B., McConnell, J.K., Hawkins, J.F., Guayasamin, R.C., Elmore, D.E., Maurer, J.A. § Ss-bCNGa: a unique member of the bacterial cyclic nucleotide gated (bCNG) channel family that gates in response to mechanical tension. European Biophysics Journal (2012) 41(12): 1003-13.
  • Malcolm, H.R., Maurer, J.A. § The Mechanosensitive Channel of Small Conductance (MscS) Superfamily: Not Just Mechanosensitive Channels Anymore. ChemBioChem (2012) 13(14): 2037-43.
  • Malcolm, H.R., Elmore, D.E, Maurer, J.A. § Mechanosensitive behavior of bacterial cyclic nucleotide gated (bCNG) ion channels: Insights into the mechanism of channel gating in the mechanosensitive channel of small conductance superfamily. Biochemical and Biophysical Research Communications (2012) 417(2): 972-976.
  • Malcolm, H.R., Heo, Y.Y., Elmore, D.E., Maurer, J.A. § Defining the Role of the Tension Sensor in the Mechanosensitive Channel of Small Conductance (MscS). Biophysical Journal. (2011) 101(2):345-352.
  • Caldwell, D.B.*, Malcolm, H.R.*, Elmore, D.E., Maurer, J.A. § Identification and experimental verification of a novel family of bacterial cyclic nucleotide-gated (bCNG) ion channels. Biochim Biophys Acta: Biomembranes. (2010) 1798(9):1750-1756.

GRANTS AND FELLOWSHIPS

  • UNF Research Enhancement Plan, “Characterizing the mechanosensitive response of Paraburkholdiera xenorvans membranes” 2019-2020
  • UNF COAS Dean’s Council Faculty Fellowship, “The identification of the pH sensor in E. coli MscS” 2017-2018
  • UNF Academic Affairs Faculty Development Scholarship Grant, “The identification of the pH sensor in E. coli MscS” 2016-2017
  • UNF Academic Technology Grant, “Acquisition of Geneious software to enhance multidisciplinary research and teaching” 2016-2017

PRESENTATIONS

Presenting author in bold, Malcolm mentee designated by

  • Johnson, S.C.  and Malcolm H.R. (2021) Poster. Exploring how varying growth conditions affect the gene expression of mechanosensitive ion channels in Escherichia coli, Showcase of Osprey Advancements in Research and Scholarship (SOARS) Jacksonville, FL, virtual.
  • Johnson, S.C.  and Malcolm H.R. (2021) Poster. Exploring how varying growth conditions affect the gene expression of mechanosensitive ion channels in Escherichia coli, Biophysical Society 65th Annual Meeting, virtual.
  • Miller, B.L., Dickinson, H.M. ¶, Wingender, B., Mikhaylova, A, Malcolm, H.R., (2020) Oral Presentation.  Mechanosensitive channels in Paraburkholderia graminis, Biophysical Society 64th National Meeting, San Diego, CA
  • Malcolm, H.R., (2019) Invited Oral Presentation. Understanding how Paraburkholderia graminis senses mechanical tension 95th Florida Annual Meeting and Exposition (FAME), Tampa, FL
  • Miller, B.L., Dickinson, H.M. ¶Malcolm, H.R., (2019) Oral Presentation. Understanding the pH modulation in E. coli mechanosensitive channel of small conductance (MscS), American Chemical Society National Meeting, Early Career Investigators in Biological Chemistry Orlando, FL
  • Miller, B.L., Malcolm, H.R., (2019) Poster. Exploring the Mechanosensitive Response of Paraburkholderia graminis Membranes, Showcase of Osprey Advancements in Research and Scholarship (SOARS) Jacksonville, FL
  • Miller, B.L., Dickinson, H.M. ¶, Malcolm, H.R., (2019) Poster. Functionally identifying members of the MscS superfamily of ion channels in Paraburkholderia membranes, Biophysical Society 63rd Annual Meeting, Baltimore, MD.

AWARDS AND HONORS

  • Outstanding Undergraduate Teaching Award Winner, UNF, 2020
  • Van Vleck Early Career Teaching Excellence Award Winner, UNF, 2018